Guilt means “a feeling of culpability for offenses” and is the opposite of righteousness.
Shame is “a condition of humiliating disgrace or disrepute” and is the opposite of glory.
And pain, of course, is the opposite to health, whether bodily or spiritual, and of pleasure.
Now we can associate St. Thomas’ effects of sin with these:
1. Guilt corresponds to debt of punishment and the evil of fault.
2. Shame, to stain on the soul and the evil of self-hatred.
3. Pain, to corruption of nature and the evil of punishment.